Enzyme polymorphism in warfarin dose management after pediatric cardiac surgery
نویسندگان
چکیده
منابع مشابه
enzyme polymorphism in warfarin dose management after pediatric cardiac surgery
conclusions the determination of warfarin dose, based on genotyping, might reduce the time to achieve stable anticoagulation of warfarin dose and length of hospital stay. patients and methods in this prospective cohort study, 200 pediatric patients, who required warfarin therapy after cardiac surgery, were enrolled and divided into two groups. for 50 cases, warfarin was prescribed based on thei...
متن کاملEnzyme Polymorphism in Warfarin Dose Management After Pediatric Cardiac Surgery
BACKGROUND Warfarin is an anticoagulant and is widely used for the prevention of thromboembolic events. Genetic variants of the enzymes that metabolize warfarin, i.e. cytochrome P450 2C9 (CYP2C9) and vitamin K epoxide reductase (VKORC1), contribute to differences in patients' responses to various warfarin doses. There is, however, a dearth of data on the role of these variants during initial an...
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Background and Objective: The present study aimed to assess the role of magnesium sulfate (MgSO4) sup-plementation after cardiac surgery in pediatric patients, evaluating the incidence of cardiac complications, such as arrhythmia. Methods: In this study, 105 children scheduled for elective cardiac surgery were randomly divided into 3 groups. The first group, as the placebo group, received sali...
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We genuinely appreciate Erek et al. (1) for their study. Extracorporeal cardiopulmonary resuscitation (ECPR) has become a widely used procedure in cardiac arrest situations. The authors should definitely admit this procedure if they use cardiac arrest after pediatric cardiac surgery, a highly catastrophic condition. We believe that their results are very successful considering that the rate of ...
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ژورنال
عنوان ژورنال: Research in Cardiovascular Medicine
سال: 2015
ISSN: 2251-9572
DOI: 10.5812/cardiovascmed.27963v2